An effective adsorbent was synthesised from nanographene oxide for the removal of the alprazolam drug from the water sample solution. The dispersive solid-phase extraction method was used with α-pyridylamine grafted nanographene oxide to extract and analyse little amounts of alprazolam in biological materials. Before beginning the experimental analysis process, it is critical to use a simple and accessible sample preparation approach. In the current study, a technique for preconcentration and measurement of trace quantities of alprazolam in aqueous samples was introduced. The pH of extraction, the amount and type of elution solvent and the period of extraction were all tuned in the alprazolam analysis technique. Analytical parameters such as the concentration factor, the limit of detection of the technique and relative standard deviation (%) were achieved as 20, 8.0 µg L-1 and 2.4%, respectively.

中文翻译：

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使用接枝α-吡啶胺的纳米氧化石墨烯分散固相法提取生物样品中的阿普唑仑。

由纳米氧化石墨烯合成了一种有效的吸附剂，用于从水样溶液中去除阿普唑仑药物。采用分散固相萃取法，以α-吡啶胺接枝纳米氧化石墨烯为原料，对生物材料中的微量阿普唑仑进行萃取分析。在开始实验分析过程之前，使用简单易用的样品制备方法至关重要。在当前的研究中，引入了一种预浓缩和测量水样中痕量阿普唑仑的技术。提取的 pH 值、洗脱溶剂的量和类型以及提取时间都在阿普唑仑分析技术中进行了调整。浓度因子等分析参数，