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Adsorption of insulin onto neonatal infusion sets: should intravenous administration of insulin to treat hyperglycemia in preterm babies on the NICU be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get to a stable insulin dose?
Molecular and Cellular Pediatrics Pub Date : 2022-12-21 , DOI: 10.1186/s40348-022-00154-y
Paola Mian 1 , Mathieu S Bolhuis 1 , J Marina Maurer 1 , Margriet van Stuijvenberg 2
Affiliation  

Insulin is used to treat neonatal hyperglycaemia when blood glucose concentrations are consistently high, and to treat neonatal diabetes. Within this brief report, a review of the existing literature is conducted to determine if intravenous administration of insulin should be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get a stable insulin dose. Within this literature search, we focused on experimental insulin adsorption data (in vitro studies).

中文翻译:

胰岛素在新生儿输液器上的吸附:治疗 NICU 早产儿高血糖症的胰岛素静脉注射应该通过静脉系统预充、添加白蛋白,还是不预充来获得稳定的胰岛素剂量?

当血糖浓度持续偏高时,胰岛素用于治疗新生儿高血糖症,以及治疗新生儿糖尿病。在这份简短的报告中,对现有文献进行了回顾,以确定是否应通过静脉系统预充、添加白蛋白或非预充以获得稳定的胰岛素剂量来进行胰岛素静脉内给药。在这项文献检索中,我们专注于实验性胰岛素吸附数据(体外研究)。
更新日期:2022-12-21
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