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Do parents vaccinated against COVID-19 protect their children from hospitalization due to COVID-19?
Journal of Tropical Pediatrics ( IF 2 ) Pub Date : 2022-12-22 , DOI: 10.1093/tropej/fmac105
Ömer Günes 1 , Belgin Gülhan 1 , Ahmet Yasin Guney 1 , Fatih Üçkardeş 2 , Seval Ozen 1 , Latife Guder 1 , Ozlem Mustafaoglu 1 , Pinar Bayraktar 1 , Aysun Yahşi 1 , Tuğba Erat 1 , Saliha Kanik-Yuksek 1 , Gulsum Iclal Bayhan 1 , Aslınur Ozkaya-Parlakay 1
Affiliation  

Objective This study aimed to determine whether parental vaccination against coronavirus disease 2019 (COVID-19) prevents hospitalization of COVID-19-infected children. Methods This study was based on data obtained from the records of pediatric patients that were followed up for virologically proven COVID-19 infection between August and October 2021, during which time the delta variant was dominant in Turkey and the children were isolating at home. Results There were 151 patients in the inpatient group and 218 in the outpatient group; the mean age was 172.5 and 145.5 months in the groups, respectively. The rates of obesity (22.5% and 6.4%, respectively, p < 0.001) and neurological–neurodevelopmental disorders (8.6% and 1.4%, respectively, p < 0.001) were significantly higher in the inpatient group than in the outpatient group. Of the outpatients’ parents, 67.4% (n = 147) were fully vaccinated vs. 38.4% (n = 58) in the inpatient group. In all, 39.7% (n = 60) of the inpatients’ parents were unvaccinated vs. 18.3% (n = 40) in the outpatient group. There was a significant correlation between the vaccination status and the patient groups (p < 0.001); it was determined that the COVID-19 infection would be mild in children if both parents were fully vaccinated. When both parents were fully vaccinated against COVID-19, the hospitalization rate decreased and the outpatient follow-up rate increased. Conclusion Having both parents fully vaccinated against COVID-19 can indirectly protect their subsequently infected children from hospitalization and the long-term effects of infection. Nonetheless, more comprehensive research on delta and non-delta variants is needed.

中文翻译:

接种 COVID-19 疫苗的父母是否可以保护他们的孩子免于因 COVID-19 住院?

目的 本研究旨在确定父母接种 2019 年冠状病毒病 (COVID-19) 疫苗是否可以防止感染 COVID-19 的儿童住院。方法 本研究基于从 2021 年 8 月至 2021 年 10 月期间对经病毒学证实的 COVID-19 感染进行随访的儿科患者的记录中获得的数据,在此期间,delta 变异在土耳其占主导地位,儿童在家中被隔离。结果住院组151例,门诊组218例;两组的平均年龄分别为 172.5 个月和 145.5 个月。住院组的肥胖率(分别为 22.5% 和 6.4%,p < 0.001)和神经-神经发育障碍率(分别为 8.6% 和 1.4%,p < 0.001)显着高于门诊组。在门诊患者的父母中,67.4% (n = 147) 完全接种了疫苗,而住院组为 38.4% (n = 58)。总共有 39.7% (n = 60) 的住院患者父母未接种疫苗,而门诊组为 18.3% (n = 40)。疫苗接种状态与患者组之间存在显着相关性 (p < 0.001);确定如果父母双方都接种了疫苗,儿童的 COVID-19 感染会很轻微。当父母双方都完全接种了 COVID-19 疫苗时,住院率下降,门诊随访率增加。结论 让父母双方全面接种 COVID-19 疫苗可以间接保护他们随后感染的孩子免于住院和感染的长期影响。尽管如此,仍需要对 delta 和非 delta 变体进行更全面的研究。
更新日期:2022-12-22
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