Effects of p450 Polymorphisms on the Clinical Outcomes of Gefitinib Treatment in Patients with Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer,Genetic Testing and Molecular Biomarkers

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Effects of p450 Polymorphisms on the Clinical Outcomes of Gefitinib Treatment in Patients with Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer
Genetic Testing and Molecular Biomarkers ( IF 1.4 ) Pub Date : 2022-12-28 , DOI: 10.1089/gtmb.2022.0070
Ruizhe Fan _{1,

2} , Jiuzhou Zhao _{1,

2} , Bo Wang _{1,

2} , Xiang Li ₁ , Yuping Guan ₃ , Pengfei Ren _{1,

2} , Rui Sun _{1,

2} , Liya Zhang ₁ , Yongjun Guo _{1,

2}

Affiliation

Aims: In this study, we determined whether different genotypes of drug-metabolizing enzymes are associated with the therapeutic effects of gefitinib in non-small cell lung cancer (NSCLC).

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