Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association with lymphoma has recently been a topic of debate. However, it is still controversial whether this risk can be attributed to the disease itself or whether it has any relationship with immunosuppressive treatment. Here, we describe the case of a patient with severe perianal hidradenitis suppurativa treated with methotrexate and infliximab, whose exacerbation with persistence of severe symptoms refractory to adequate treatment led to the diagnosis of diffuse large non-Hodgkin B-cell lymphoma. It was decided to perform a colostomy to improve perianal sepsis, and immunochemotherapy was proposed.
GE Port J Gastroenterol

中文翻译：

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难治性化脓性汗腺炎：需要考虑的诊断

化脓性汗腺炎是一种与多种合并症相关的慢性炎症性疾病，其与淋巴瘤的关联最近成为争论的话题。然而，这种风险是否可以归因于疾病本身，或者是否与免疫抑制治疗有任何关系，目前仍存在争议。在这里，我们描述了一名严重肛周化脓性汗腺炎患者的病例，该患者接受了甲氨蝶呤和英夫利昔单抗治疗，其病情加重并伴有经充分治疗难以治愈的持续性严重症状，最终被诊断为弥漫性大非霍奇金 B 细胞淋巴瘤。决定进行结肠造口术以改善肛周脓毒症，并提出免疫化疗。
GE Port J 胃肠醇