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Association between maternal plasma total antioxidant capacity and dietary antioxidants intake with birth size outcomes.
Journal of Tropical Pediatrics ( IF 2 ) Pub Date : 2022-12-05 , DOI: 10.1093/tropej/fmac112
Nafiseh Shokri-Mashhadi 1 , Mehri Khoshhali 2 , Motahar Heidari-Beni 3 , Roya Kelishadi 2
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BACKGROUND Maternal antioxidants intake and plasma total antioxidant capacity (TAC) concentration during pregnancy might influence on birth outcomes. This study was conducted to determine the association between dietary antioxidants intake and plasma TAC during pregnancy with birth outcomes. METHODS Overall, 220 mother-infant pairs were recruited in the first trimester of pregnancy. Maternal whole blood was collected and TAC was determined by the ELISA kit. Food frequency questionnaire was used to collect information regarding usual dietary intake. Birth size measurements including birth weight, length and head circumference were measured according to standardized protocols. RESULTS Energy-adjusted intake of beta-carotene in the first trimester of gestation [beta (SE) = 0.0002 (0.00008); p = 0.016] and energy-adjusted intake of vitamin E in third trimester of pregnancy [beta (SE) = -0.31 (0.15); p = 0.046] had significantly positive and negative associations with birth length, respectively. The maternal plasma TAC was positively correlated with birth weight in both unadjusted and adjusted models [beta (SE) = 2.75 (1.35); p = 0.043 and beta (SE) = 3.43 (1.50); p = 0.023, respectively]. In addition, the adjusted model showed a significant positive relationship between the maternal plasma TAC and birth length [beta (SE) = 0.023 (0.009); p = 0.01]. CONCLUSION This study showed the positive association of maternal plasma TAC with birth weight and length. Moreover, maternal dietary intake of beta-carotene in the first trimester and vitamin E in the third trimester of pregnancy had significant positive and negative correlations with birth length, respectively.

中文翻译:

母体血浆总抗氧化能力和膳食抗氧化剂摄入量与出生大小结果之间的关联。

背景 孕期母亲抗氧化剂摄入量和血浆总抗氧化能力 (TAC) 浓度可能会影响分娩结果。本研究旨在确定妊娠期间膳食抗氧化剂摄入量和血浆 TAC 与分娩结局之间的关联。方法 总体而言,在妊娠的前三个月招募了 220 对母婴。收集母体全血并通过 ELISA 试剂盒测定 TAC。食物频率问卷用于收集有关日常饮食摄入量的信息。包括出生体重、身长和头围在内的出生尺寸测量值根据标准化方案进行测量。结果 妊娠早期 β-胡萝卜素的能量调整摄入量 [β (SE) = 0.0002 (0.00008);p = 0。016] 和妊娠晚期维生素 E 的能量调整摄入量 [beta (SE) = -0.31 (0.15); p = 0.046] 分别与出生长度有显着正相关和负相关。在未调整和调整模型中,母体血浆 TAC 与出生体重呈正相关 [β (SE) = 2.75 (1.35);p = 0.043 和 beta (SE) = 3.43 (1.50);p = 0.023,分别]。此外,调整后的模型显示母体血浆 TAC 与出生长度之间存在显着的正相关关系 [beta (SE) = 0.023 (0.009);p = 0.01]。结论 本研究表明母体血浆 TAC 与出生体重和身长呈正相关。而且,
更新日期:2022-12-05
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