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A new role for monomeric ParA/Soj in chromosome dynamics in Bacillus subtilis
MicrobiologyOpen ( IF 3.4 ) Pub Date : 2023-01-16 , DOI: 10.1002/mbo3.1344
David M Roberts 1
Affiliation  

ParABS (Soj-Spo0J) systems and SMC complexes are critical mediators of chromosome dynamics in a range of bacteria. In this commentary, I review the roles of these systems in Bacillus subtilis, as well as discuss a recent study that implicates a monomeric variant of ParA/Soj as a novel regulator of SMC release and redistribution after loading onto the DNA, a process that is critical for chromosome reorganization during axial filament formation in early sporulation.

中文翻译:

单体 ParA/Soj 在枯草芽孢杆菌染色体动力学中的新作用

ParABS (Soj-Spo0J) 系统和 SMC 复合物是一系列细菌中染色体动力学的关键介质。在这篇评论中,我回顾了这些系统在枯草芽孢杆菌中的作用,并讨论了最近的一项研究,该研究将 ParA/Soj 的单体变体作为加载到 DNA 后 SMC 释放和再分配的新型调节剂,这一过程是在早期孢子形成的轴丝形成过程中对染色体重组至关重要。
更新日期:2023-01-17
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