Intraoperative neuromonitoring has been a valuable tool for ensuring the functional integrity of vital neural structures by providing real-time feedback to the operative team during procedures where neurological structures are at risk. Commonly used intravenous and inhaled anesthetic drugs are known to affect waveform parameters measured with various intraoperative neuromonitoring modalities. While the concept of opioid-sparing multimodal analgesia has gained popularity in recent years, the impact of such a strategy on intraoperative neuromonitoring remains poorly characterized, in contrast to the more well-established concepts and literature regarding the effects of other hypnotic agents on neuromonitoring quality. The purpose of this focused review is to provide an overview of the clinical evidence pertaining to the pharmacological interaction of certain multimodal analgesics with routine intraoperative neuromonitoring modalities.

术中神经监测已成为确保重要神经结构功能完整性的重要工具，它可以在神经结构面临风险的手术过程中向手术团队提供实时反馈。已知常用的静脉注射和吸入麻醉药物会影响各种术中神经监测方式测量的波形参数。尽管近年来，少用阿片类药物的多模式镇痛概念越来越流行，但与其他催眠药对神经监测质量影响的更成熟的概念和文献相比，这种策略对术中神经监测的影响仍然知之甚少。 。本次重点综述的目的是概述某些多模式镇痛药与常规术中神经监测方式的药理学相互作用的临床证据。