We aim to evaluate the clinical course and outcome of cases with a prenatal diagnosis of ectopia cordis in our center. In this retrospective study, we analyzed clinical variables including gestational age at diagnosis, maternal age, associated cardiac, extracardiac, genetic anomalies and, outcome in prenatally diagnosed ectopia cordis cases in our tertiary referral center. Eight ectopia cordis cases from seven pregnancies were included in the study. All fetuses had complete type of ectopia cordis and pentalogy of Cantrell. Five multiple pregnancies were found, four were twin pregnancies (three dichorionic diamniotic, one monochorionic monoamniotic) and one was triplet (trichorionic triamniotic). In the monochorionic monoamniotic twin pregnancy, both fetuses have pentalogy of Cantrell. Two cases had intracardiac structural defects including Tetralogy of Fallot and hypoplastic right heart syndrome. Three pregnancies were terminated, four cases delivered alive could not survive beyond the neonatal period. The striking feature in our study is its association with multiple pregnancies.

中文翻译：

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八例心异位胎儿的临床特征及结局评价 来自胎儿心脏病学中心的一项研究

我们旨在评估我们中心产前诊断为心异位病例的临床过程和结果。在这项回顾性研究中，我们分析了临床变量，包括诊断时的胎龄、产妇年龄、相关的心脏、心外、遗传异常，以及我们三级转诊中心产前诊断的心异位病例的结局。来自 7 例妊娠的 8 例心异位病例被纳入研究。所有胎儿均有完全型心异位和Cantrell五联症。发现了 5 例多胎妊娠，4 例是双胞胎妊娠（3 例是双绒毛膜双羊膜囊，1 例是单绒毛膜单羊膜囊），1 例是三胞胎（毛绒毛膜三羊膜囊）。单绒毛膜单羊膜双胎妊娠，双胎均有坎特雷尔五联症。2例合并法洛四联症、右心发育不全综合征等心内结构缺陷。终止妊娠3例，活产4例不能活过新生儿期。我们研究中的显着特征是它与多胎妊娠的关联。