The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac₂, and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions.

中文翻译：

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碱不稳定神经节苷脂

讨论了一组经弱碱处理修饰的神经节苷脂的结构和性质。我们将介绍在第 9 位携带N-乙酰神经氨酸O-乙酰化 Neu5,9Ac ₂的神经节苷脂和携带形成内酯环的唾液酸的神经节苷脂的出现和结构。从生化数据开始，我们将讨论这些神经节苷脂在细胞信号传导和大脑功能维持过程中可能发挥的生化作用。