The crystal structure of besifloxacin hydrochloride has been solved and refined using synchrotron X-ray powder diffraction data, and optimized using density functional theory techniques. Besifloxacin hydrochloride crystallizes in space group P1 (#1) with a = 5.36596(8), b = 10.3234(4), c = 17.9673(14) Å, α = 98.122(5), β = 92.9395(9), γ = 96.1135(3)°, V = 977.483(13) Å3, and Z = 2. The crystal structure is approximately centrosymmetric. Strong N–H⋯Cl hydrogen bonds form a corrugated ladder-like chain along the a-axis. The carboxylic acid group in each independent cation acts as the donor in a strong intramolecular O–H⋯O hydrogen bond to an adjacent carbonyl group. The powder pattern has been submitted to ICDD for inclusion in the Powder Diffraction File™ (PDF®).

盐酸贝西沙星的晶体结构已利用同步加速器 X 射线粉末衍射数据解析和细化，并利用密度泛函理论技术进行了优化。盐酸贝西沙星在空间群P 1 (#1) 中结晶， a = 5.36596(8)，b = 10.3234(4)，c = 17.9673(14) Å，α = 98.122(5)，β = 92.9395(9)，γ = 96.1135(3)°, V = 977.483(13) Å 3 , Z = 2。晶体结构近似中心对称。强 N–H⋯Cl 氢键沿着a 方向形成波纹梯状链-轴。每个独立阳离子中的羧酸基团在与相邻羰基的强分子内 O–H⋯O 氢键中充当供体。粉末图案已提交给 ICDD 以包含在 Powder Diffraction File™ (PDF®) 中。