Genomics, an interdisciplinary field of biology on the structure, function, and evolution of genomes, has revolutionized many subdisciplines of life sciences, including my field of evolutionary biology, by supplying huge data, bringing high-throughput technologies, and offering a new approach to biology. In this review, I describe what I have learned from genomics and highlight the fundamental knowledge and mechanistic insights gained. I focus on three broad topics that are central to evolutionary biology and beyond—variation, interaction, and selection—and use primarily my own research and study subjects as examples. In the next decade or two, I expect that the most important contributions of genomics to evolutionary biology will be to provide genome sequences of nearly all known species on Earth, facilitate high-throughput phenotyping of natural variants and systematically constructed mutants for mapping genotype–phenotype–fitness landscapes, and assist the determination of causality in evolutionary processes using experimental evolution.

基因组学是一个关于基因组结构、功能和进化的跨学科生物学领域，通过提供大量数据、带来高通量技术并提供一种新方法，彻底改变了生命科学的许多分支学科，包括我的进化生物学领域。生物学。在这篇评论中，我描述了我从基因组学中学到的东西，并强调了所获得的基础知识和机制见解。我专注于进化生物学及其他领域的三个核心主题——变异、相互作用和选择——并主要使用我自己的研究和研究主题作为例子。在未来一两年内，我预计基因组学对进化生物学最重要的贡献将是提供地球上几乎所有已知物种的基因组序列，促进自然变异的高通量表型分析以及系统地构建突变体以绘制基因型-表型图–健身景观，并利用实验进化协助确定进化过程中的因果关系。