OBJECTIVE Limited data are available on posttraumatic stress symptoms (PTSS) among COVID-19 survivors. This study aimed to contribute to this knowledge base. METHODS PTSS among COVID-19 survivors who had been hospitalized were investigated. Patients were identified as COVID-19 positive at hospital admission. COVID-19 survivors were surveyed with the Posttraumatic Stress Disorder Checklist (PCL-5) between March and October 2020 at 5- and 12-month postdischarge follow-up points. RESULTS Of 411 patients, 331 (81%) survived to hospital discharge. Of these survivors, 83 (25%) completed the PCL-5 at the 5-month follow-up. Of those patients, 12 (14%) screened positive for PTSS. At the 12-month follow-up, four of eight patients remained PTSS positive. Mean age of follow-up participants was 62±15 years; 47% were women, 65% were White, and 63% were Hispanic. PTSS-positive patients were predominantly non-White (67% vs. 30%, p=0.02), and although the differences were not statistically significant, these patients tended to be younger (56 vs. 63 years, p=0.08) and have shorter intensive care unit stays (2.0 vs. 12.5 days, p=0.06). PTSS-positive and PTSS-negative groups did not differ significantly in prehospitalization neurological diagnoses (11% vs. 8%), psychiatric diagnoses (17% vs. 21%), and intensive care admission status (25% vs. 25%). More patients in the PTSS-positive group had returned to the emergency department (50% vs. 14%, p<0.01) and reported fatigue at follow-up (100% vs. 42%, p<0.001). In the multivariate logistic regression model, non-White race (OR=11, 95% CI=2-91) and returning to the emergency department (OR=19, 95% CI=3-252) were associated with PTSS-positive status. CONCLUSION PTSS were twice as common among hospitalized COVID-19 survivors than among those in the general population.

中文翻译：

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COVID-19 幸存者住院后的创伤后应激症状。

目标 关于 COVID-19 幸存者创伤后应激症状 (PTSS) 的数据有限。本研究旨在为这一知识库做出贡献。方法 对住院的 COVID-19 幸存者进行 PTSS 调查。患者入院时被诊断为 COVID-19 阳性。2020 年 3 月至 10 月期间，在出院后 5 个月和 12 个月的随访点，对 COVID-19 幸存者进行了创伤后应激障碍检查表 (PCL-5) 调查。结果 411 名患者中，331 名 (81%) 存活至出院。在这些幸存者中，83 人 (25%) 在 5 个月的随访中完成了 PCL-5。在这些患者中，12 名 (14%) 的 PTSS 筛查结果呈阳性。在 12 个月的随访中，8 名患者中有 4 名仍保持 PTSS 阳性。随访参与者的平均年龄为 62±15 岁；47% 是女性，65% 是白人，63% 是西班牙裔。PTSS 阳性患者主要是非白人（67% vs. 30%，p=0.02），虽然差异不具有统计学意义，但这些患者往往更年轻（56 岁 vs. 63 岁，p=0.08）并且有重症监护病房停留时间较短（2.0 天与 12.5 天，p=0.06）。PTSS 阳性组和 PTSS 阴性组在入院前神经系统诊断（11% vs. 8%）、精神科诊断（17% vs. 21%）和重症监护入院状态（25% vs. 25%）方面没有显着差异。PTSS 阳性组中有更多患者返回急诊科（50% vs. 14%，p<0.01），并在随访时报告疲劳（100% vs. 42%，p<0.001）。在多变量逻辑回归模型中，非白人种族（OR=11，95% CI=2-91）和返回急诊室（OR=19，95% CI=3-252）与 PTSS 阳性状态相关。结论 住院的 COVID-19 幸存者中 PTSS 的发生率是普通人群的两倍。