Although continuous improvement in the treatment outcome of localized gastric cancer has been achieved through early screening, diagnosis, and treatment and the active application of surgery and adjuvant chemotherapy, the necessity of adjuvant radiotherapy (RT) remains controversial. In this review, based on the results of two recently published randomized phase III studies (Adjuvant Chemoradiation Therapy In Stomach Cancer 2 and ChemoRadiotherapy after Induction chemoTherapy of Cancer in the Stomach) and a meta-analysis of six randomized trials including these two studies, the role of adjuvant RT in gastric cancer was evaluated and discussed, especially in patients who underwent curative gastrectomy with D2 lymphadenectomy. This article also reported the possible indications for adjuvant RT in the current clinical situation and in future research to enable patient-specific treatments according to the risk of recurrence.

中文翻译：

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辅助放疗在胃癌中的作用。

尽管局限性胃癌通过早期筛查、早诊早治、积极应用手术和辅助化疗，治疗效果不断改善，但辅助放疗的必要性仍存在争议。在这篇综述中，基于最近发表的两项随机 III 期研究（胃癌辅助放化疗 2 和胃癌诱导化疗后放化疗）的结果以及对包括这两项研究的六项随机试验的荟萃分析，评估和讨论了辅助放疗在胃癌中的作用，尤其是在接受根治性胃切除术和 D2 淋巴结清扫术的患者中。