COVID-19 is a transmissible respiratory and multisystem disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Viral transmission occurs mainly through the spread of salivary droplets or aerosol from an infected subject. Studies suggest that salivary viral load is correlated with disease severity and probability of transmission. Cetylpyridinium chloride mouthwash has been found to be effective in reducing salivary viral load. The aim of this systematic review of randomized controlled trials is to evaluate the efficacy of the mouthwash ingredient cetylpyridinium chloride on salivary viral load in SARS-CoV-2 infection.

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西吡氯铵漱口水对 SARS-CoV-2 的疗效：随机对照试验的系统评价

COVID-19 是由严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 引起的传染性呼吸道和多系统疾病。病毒传播主要通过受感染对象的唾液飞沫或气溶胶传播发生。研究表明，唾液病毒载量与疾病严重程度和传播概率相关。已发现氯化十六烷基吡啶漱口水可有效降低唾液病毒载量。这项对随机对照试验进行系统评价的目的是评估漱口水成分氯化十六烷基吡啶对 SARS-CoV-2 感染患者唾液病毒载量的疗效。