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Solid Organ Transplantation for Children With Neurodevelopmental Disabilities—Ethical Considerations and a Call for Clarity
Seminars in Pediatric Neurology ( IF 2.7 ) Pub Date : 2023-02-22 , DOI: 10.1016/j.spen.2023.101035
Kyla M Tolliver 1 , John J Parent 2 , Michael J Hobson 3
Affiliation  

Pediatric transplant centers are faced with the difficult task of maximizing the benefit of organs donated for transplantation while also ensuring that all patients undergoing transplant evaluation are fairly considered for this life-saving therapy. Children with neurodevelopmental disabilities are a complex patient population that on occasion may face the need for a solid organ transplant. Several concerns exist regarding transplantation in this population, yet standard transplant inclusion and exclusion criteria do not exist. Here we explore important factors regarding organ transplantation for children with neurodevelopmental disorders, including patient outcomes, quality of life considerations, and the fundamental ethical principles underlying this complex medical decision-making.



中文翻译:

神经发育障碍儿童的实体器官移植——伦理考虑和澄清呼吁

儿科移植中心面临着一项艰巨的任务,即最大限度地利用捐献用于移植的器官,同时确保所有接受移植评估的患者都被公平地考虑用于这种挽救生命的治疗。患有神经发育障碍的儿童是一个复杂的患者群体,有时可能需要进行实体器官移植。关于这一人群的移植存在一些担忧,但不存在标准的移植纳入和排除标准。在这里,我们探讨了神经发育障碍儿童器官移植的重要因素,包括患者结果、生活质量考虑因素,以及这一复杂医疗决策背后的基本伦理原则。

更新日期:2023-02-22
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