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Last twenty-years activity of cardiovascular tissue banking in Barcelona
Cell and Tissue Banking ( IF 1.5 ) Pub Date : 2023-02-27 , DOI: 10.1007/s10561-022-10059-9
C Castells-Sala 1, 2, 3 , M L Pérez 1, 4 , E Agustí 1, 4 , A Aiti 1 , E Tarragona 1 , A Navarro 5 , J Tabera 1, 2 , O Fariñas 1, 2 , J L Pomar 6 , A Vilarrodona 1, 4
Affiliation  

The Barcelona Tissue Bank was established from the merge of two previous multi-tissue banks. Potential donors are screened by Donor Center staff and multi-tissue retrieval is performed by specialized own teams. Tissue processing and preservation is performed in clean room facilities by specialised personnel. After quality control of both donor and all tissues results, the heart valves and vascular segments are stored until medical request. The aim of this report is to present the cardiovascular tissue activity and retrospectively evaluate the outcomes of the changes performed in last 20 years. Cardiovascular tissue from 4088 donors was received, specifically 3115 hearts and 2095 vascular segments were processed and evaluated. A total of 48% of the aortic valves, 68% of the pulmonary valves and 75% of the vascular segments were suitable for transplant. The main reason for discarding tissue was macroscopic morphology followed by microbiological results, for both valves and arteries. Altogether, 4360 tissues were distributed for transplantation: 2032 (47%) vascular segments, 1545 (35%) pulmonary valves and 781 (18%) aortic valves. The most common indication for aortic valve surgery was the treatment of endocarditis, while for pulmonary valves, it was congenital malformation reconstruction. Vascular segments were mainly used for reconstruction after ischemia. During this period, a number of changes were made with the goal of enhancing tissue quality, safety and efficacy. These improvements were achieved through the use of a new antibiotic cocktail, increasing of donor age criteria and changing the microbiological control strategy.



中文翻译:

巴塞罗那心血管组织银行过去二十年的活动

巴塞罗那组织银行是由两家先前的多组织银行合并而成。潜在的捐赠者由捐赠者中心的工作人员筛选,多组织检索由专门的团队执行。组织处理和保存由专业人员在洁净室设施中进行。在对供体和所有组织进行质量控制后,心脏瓣膜和血管段会被储存起来,直到医疗要求为止。本报告的目的是介绍心血管组织活动,并回顾性评估过去 20 年发生的变化的结果。收到来自 4088 名供体的心血管组织,具体处理和评估了 3115 颗心脏和 2095 个血管段。总计48%的主动脉瓣,68%的肺动脉瓣和75%的血管段适合移植。对于瓣膜和动脉,丢弃组织的主要原因是宏观形态,其次是微生物学结果。总共分配了 4360 个组织用于移植:2032 个(47%)血管段、1545 个(35%)肺动脉瓣和 781 个(18%)主动脉瓣。主动脉瓣手术最常见的适应症是治疗心内膜炎,而肺动脉瓣手术最常见的适应症是先天性畸形重建。血管段主要用于缺血后的重建。在此期间,以提高组织质量、安全性和有效性为目标,进行了许多更改。这些改进是通过使用一种新的抗生素混合物实现的,

更新日期:2023-02-28
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