Abstract

This review considers the main approaches to the preparation of covalent organic perchlorates (COPs) and their chemical properties. COPs can be synthesized by the reactions of chlorine(VII) oxide with alcohols, alcoholates, and epoxides, the interaction of perchlorate anion with epoxides and alkenes, occurring upon activation of substrates by various electrophiles, and the oxidative nucleophilic substitution of alkyl halides. The reactivity of COPs is determined by the high nucleofugity of the perchlorate fragment, which makes them extremely active reagents in nucleophilic and electrophilic aromatic substitution reactions. A new direction in the study of the chemical properties of COPs is their interaction with nitriles, which is a modified version of the Ritter reaction.

中文翻译：

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共价有机高氯酸盐：合成与性质

摘要

本综述考虑了制备共价有机高氯酸盐 (COP) 的主要方法及其化学性质。COP 可以通过氧化氯 (VII) 与醇、醇化物和环氧化物的反应、高氯酸根阴离子与环氧化物和烯烃的相互作用、各种亲电子试剂激活底物以及烷基卤化物的氧化亲核取代反应来合成。COPs 的反应性取决于高氯酸盐片段的高离核性，这使得它们在亲核和亲电芳族取代反应中成为极其活跃的试剂。COPs 化学性质研究的一个新方向是它们与腈类的相互作用，这是 Ritter 反应的改进版。