Objective Adverse childhood experiences, ranging from childhood trauma to neglect or mistreatment, show associations with alcohol dependence in adulthood. Alcohol researchers have not yet clearly demonstrated the potential impact of childhood maltreatment on everyday drinking in alcohol consumers who do not have an alcohol use disorder (AUD). This study examined whether a history of childhood neglect results in differential ratings of stress, affect, and desire to drink, during typical alcohol consumption in moderate to heavy drinkers without an AUD. Methods The parent study from which these analyses were generated recruited overall healthy, albeit moderate to heavy alcohol users who fell above National Institute on Alcohol Abuse and Alcoholism (NIAAA) classifications for low-risk drinking. Childhood Trauma Questionnaire (CTQ) responses were collected, and real-time surveys were collected in participants' natural environments approximately every three hours between 9 a.m. and 9 p.m. using iPhones equipped with a study-created application probing stress, affect, and desire for alcohol, while participants followed their typical drinking routine (3 days) and during a brief period of imposed abstinence (3 days). Results Thirty-six participants averaging 41 years of age and consuming an average of 17 (±5) drinks per week participated in this study. CTQ responses showed low prevalence of childhood abuse, but moderate to high emotional (M = 17.39, SD = 6.77) and physical neglect (M = 11.11, SD = 3.31) scores. Multilevel modeling revealed significantly higher stress and lower affect ratings among participants reporting higher physical neglect. Alcohol consumption was significantly associated with decreased stress, and increased affect and desire for alcohol. A significant interaction showed that as childhood physical neglect ratings increased, the benefits observed following drinking (of decreased stress, and increased affect and desire for alcohol) were reduced. Conclusions These results suggest that moderate to heavy healthy daily drinkers with histories of greater childhood physical neglect experience poorer mood and higher stress on a daily basis, with smaller improvement experienced from drinking alcohol. Among moderate to heavy daily drinkers without an AUD, those with greater childhood physical neglect experience poorer mood and higher stress on a daily basis, and have smaller improvements in stress, affect and desire while/following drinking alcohol than those with less childhood physical neglect.

中文翻译：

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童年忽视与习惯性饮酒者的低影响和高压力有关。

目标 不良的童年经历，从童年创伤到忽视或虐待，表明与成年期的酒精依赖有关。酒精研究人员尚未明确证明童年虐待对没有酒精使用障碍 (AUD) 的酒精消费者日常饮酒的潜在影响。本研究调查了在没有 AUD 的中度至重度饮酒者的典型饮酒过程中，童年被忽视的历史是否会导致压力、影响和饮酒欲望的不同评级。方法 生成这些分析的父研究招募了总体健康但中度至重度饮酒者，他们高于国家酒精滥用和酒精中毒研究所 (NIAAA) 的低风险饮酒分类。收集了儿童创伤问卷 (CTQ) 的回复，并在上午 9 点到晚上 9 点之间大约每三个小时在参与者的自然环境中收集实时调查，使用配备研究创建的应用程序的 iPhone 探测压力、影响和对酒精的渴望，而参与者则遵循他们典型的饮酒习惯（3 天）并在短暂的强制戒酒期间（3 天）。结果 36 名平均年龄 41 岁且每周平均饮用 17 (±5) 杯酒的参与者参与了这项研究。CTQ 反应显示童年虐待的流行率较低，但情绪（M = 17.39，SD = 6.77）和身体忽视（M = 11.11，SD = 3.31）得分为中度至高。多层次模型显示，在报告身体忽视程度较高的参与者中，压力明显更高，影响评级更低。饮酒与减轻压力、增加对酒精的影响和欲望显着相关。一项重要的相互作用表明，随着儿童身体忽视评级的增加，饮酒后观察到的好处（减少压力，增加对酒精的影响和渴望）减少。结论 这些结果表明，中度至重度健康的日常饮酒者如果有童年时期身体忽视的历史，他们每天都会经历较差的情绪和较高的压力，饮酒带来的改善较小。在没有 AUD 的中度到重度日常饮酒者中，