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Maternal and neonatal outcomes following SARS-CoV-2 infection
Seminars in Fetal and Neonatal Medicine ( IF 3 ) Pub Date : 2023-03-11 , DOI: 10.1016/j.siny.2023.101428
Lillian B Boettcher 1 , Torri D Metz 1
Affiliation  

Infection with SARS-CoV-2 causing COVID-19 in pregnancy is known to confer risks to both the pregnant patient and fetus. A review of the current literature demonstrates that pregnant individuals with SARS-CoV-2 infection are at risk for higher composite morbidity, intensive care unit admission, ventilatory support, pre-eclampsia, preterm birth, and neonatal intensive care unit admissions compared to pregnant individuals without SARS-CoV-2. Worse obstetric morbidity and mortality generally correlate with the severity of COVID-19. Comorbidities such as diabetes increase the risk of severe COVID-19. An increased risk of stillbirth appears to be predominantly confined to pregnancies affected in the Delta variant time period. Further, vaccination against SARS-CoV-2 has been demonstrated to be safe and effective in pregnancy and while breastfeeding. Therefore, continued counseling encouraging vaccination remains imperative. The long-term maternal and neonatal consequences of pregnancies affected by SARS-CoV-2 remain unknown, and therefore continued research in this regard is warranted.



中文翻译:

SARS-CoV-2 感染后的母婴结局

众所周知,在怀孕期间感染 SARS-CoV-2 导致 COVID-19 会给孕妇和胎儿带来风险。对当前文献的回顾表明,与孕妇相比,感染 SARS-CoV-2 的孕妇有更高的复合发病率、入住重症监护病房、通气支持、先兆子痫、早产和新生儿重症监护病房的风险没有 SARS-CoV-2。较差的产科发病率和死亡率通常与 COVID-19 的严重程度相关。糖尿病等合并症会增加患重症 COVID-19 的风险。死产风险增加似乎主要局限于受三角洲变异时间段影响的妊娠。此外,已证明针对 SARS-CoV-2 的疫苗接种在怀孕期间和哺乳期间是安全有效的。因此,继续进行鼓励接种疫苗的咨询仍然势在必行。受 SARS-CoV-2 影响的妊娠对母婴的长期后果仍然未知,因此有必要在这方面继续进行研究。

更新日期:2023-03-11
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