In this study, the inverse solution with a single dipole was computed to localize the premature ventricular contraction (PVC) origin from long term multiple leads ECG measurements on fourteen patients. The stability of the obtained results was studied with respect to the preprocessing of signals used as an input to the inverse solution and the complexity of the torso model. Two methods were used for the baseline drift removal. After an averaging of the heartbeats, the influence of the retention or elimination of the remaining offset at the beginning of the PVC signal was examined. The inverse computations were performed using both homogeneous and inhomogeneous patient-specific torso models. It was shown that the remaining offset in the averaged signals at the beginning of the PVC signal had the most significant impact on the stability of the resulting position within the ventricles. Its elimination stabilizes the location of the results, decreases the sensitivity to the torso model complexity and decreases the sensitivity to the primary baseline drift removal method. The additional offset correction decreased the mean distance between the results for all patients from 17-18 mm to 1-2 mm, regardless of the baseline drift removal method or the torso model complexity.

中文翻译：

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心电图偏移校正对临床数据室性早搏起源定位的重要性

在这项研究中，计算了具有单个偶极子的逆解，以定位来自 14 名患者的长期多导联 ECG 测量的室性早搏 (PVC) 起源。针对用作逆解输入的信号的预处理和躯干模型的复杂性，研究了所得结果的稳定性。两种方法用于去除基线漂移。在心跳平均后，检查了 PVC 信号开始时剩余偏移的保留或消除的影响。使用均质和非均质患者特定躯干模型进行逆计算。结果表明，PVC 信号开始时平均信号中的剩余偏移量对心室内所得位置的稳定性具有最显着的影响。它的消除稳定了结果的位置，降低了对躯干模型复杂性的敏感性，并降低了对主要基线漂移去除方法的敏感性。额外的偏移校正将所有患者的结果之间的平均距离从 17-18 毫米减少到 1-2 毫米，无论基线漂移去除方法或躯干模型的复杂性如何。