ABSTRACT

Siblings of individuals with neurodevelopmental conditions (NDCs) are exposed to unique family environments and experience a range of psychosocial risk and resilience factors. Networks of self-reported risk, resilience, and neuropsychiatric variables were estimated for siblings of individuals with (n = 235) and without (n = 480) NDCs (N = 715, mean age 22.40 years, 76% female, 74% White Caucasian). The NDC group reported more depressive (g = 0.39) and anxious (g = 0.43) symptoms than controls, and 71.5% of the NDC group reported at least one neuropsychiatric diagnosis compared to 36.9% of controls. Self-reported sleep and post-traumatic stress disorders were high amongst NDC siblings. Everyday executive functioning difficulties (cognitive inflexibility, hyperactivity/impulsivity) and emotion dysregulation were the most influential transdiagnostic risk factors for poorer functioning within the NDC group network.

摘要

患有神经发育疾病 (NDC) 的人的兄弟姐妹会暴露在独特的家庭环境中，并经历一系列社会心理风险和恢复力因素。对有（n  = 235）和没有（n  = 480）NDC（N = 715，平均年龄 22.40 岁，76% 为女性，74% 为白种人）。NDC 组比对照组报告更多的抑郁 (g = 0.39) 和焦虑 (g = 0.43) 症状，71.5% 的 NDC 组报告至少一种神经精神诊断，而对照组为 36.9%。自我报告的睡眠和创伤后应激障碍在 NDC 兄弟姐妹中很高。日常执行功能困难（认知不灵活、多动/冲动）和情绪失调是 NDC 组网络内功能较差的最具影响力的跨诊断风险因素。