Immunohistochemical staining patterns of markers for neurogenesis staging were compared at the identical stage of cerebellar histogenesis between ferrets (aged 20 days) and mice (aged 10 days). Proliferating cell nuclear antigen (PCNA) immunostaining was observed largely in the granular precursors of the external granular layer (EGL) in both ferrets and mice. PCNA-immunostaining was also found in brain lipid-binding protein-immunopositive cells in the internal granular layer and was more abundant in ferrets than in mice. Paired box 6 immunostaining appeared largely in the EGL granular precursors in mice, whereas it emerged in the migrating/differentiating granular precursors in ferrets. These findings revealed that the types and neurogenesis stages of the EGL granular precursors detected by immunohistochemical markers differed between ferrets and mice.

中文翻译：

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雪貂和小鼠早产小脑神经发生分期的免疫组织化学标记的差异染色模式

在雪貂（20 天龄）和小鼠（10 天龄）小脑组织发生的同一阶段，比较了神经发生分期标记物的免疫组织化学染色模式。增殖细胞核抗原（PCNA）免疫染色主要在雪貂和小鼠的外颗粒层（EGL）的颗粒前体中观察到。PCNA 免疫染色也在内部颗粒层的脑脂质结合蛋白免疫阳性细胞中发现，并且在雪貂中比在小鼠中更丰富。配对框 6 免疫染色主要出现在小鼠的 EGL 颗粒前体中，而它出现在雪貂的迁移/分化颗粒前体中。