Progress in biological cancer characterization, targeted systemic therapies and multimodality treatment strategies have shifted the goals of radiotherapy for spinal metastases from short-term palliation to long-term symptom control and prevention of compilations. This article gives an overview of the spine stereotactic body radiotherapy (SBRT) methodology and clinical results of SBRT in cancer patients with painful vertebral metastases, metastatic spinal cord compression, oligometastatic disease and in a reirradiation situation. Outcomes after dose-intensified SBRT are compared with results of conventional radiotherapy and patient selection criteria will be discussed. Though rates of severe toxicity after spinal SBRT are low, strategies to minimize the risk of vertebral compression fracture, radiation induced myelopathy, plexopathy and myositis are summarized, to optimize the use of SBRT in multidisciplinary management of vertebral metastases.

癌症生物学表征、靶向全身治疗和多模式治疗策略的进展已将脊柱转移瘤放疗的目标从短期姑息治疗转变为长期症状控制和预防复发。本文概述了脊柱立体定向体部放射治疗 (SBRT) 方法和 SBRT 在患有疼痛性椎体转移、转移性脊髓压迫、寡转移性疾病和处于再照射情况下的癌症患者中的临床结果。将剂量强化 SBRT 后的结果与常规放疗的结果进行比较，并将讨论患者选择标准。虽然脊柱 SBRT 后严重毒性的发生率很低，但将椎体压缩性骨折、辐射诱发的脊髓病风险降至最低的策略，