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Integration of Feedforward and Feedback Information Streams in the Modular Architecture of Mouse Visual Cortex
Annual Review of Neuroscience ( IF 13.9 ) Pub Date : 2023-03-27 , DOI: 10.1146/annurev-neuro-083122-021241
Andreas Burkhalter 1 , Rinaldo D D'Souza 1 , Weiqing Ji 1 , Andrew M Meier 2
Affiliation  

Radial cell columns are a hallmark feature of cortical architecture in many mammalian species. It has long been held, based on the lack of orientation columns, that such functional units are absent in rodent primary visual cortex (V1). These observations led to the view that rodent visual cortex has a fundamentally different network architecture than that of carnivores and primates. While columns may be lacking in rodent V1, we describe in this review that modular clusters of inputs to layer 1 and projection neurons in the layers below are prominent features of the mouse visual cortex. We propose that modules organize thalamocortical inputs, intracortical processing streams, and transthalamic communications that underlie distinct sensory and sensorimotor functions.

中文翻译:

小鼠视觉皮层模块化架构中前馈和反馈信息流的集成

放射状细胞柱是许多哺乳动物物种皮质结构的标志性特征。长期以来,由于缺乏定向柱,人们一直认为啮齿动物初级视觉皮层(V1)中不存在此类功能单元。这些观察结果表明,啮齿动物视觉皮层的网络结构与食肉动物和灵长类动物的网络结构根本不同。虽然啮齿类动物 V1 可能缺乏柱,但我们在这篇综述中描述了第 1 层的输入模块簇和下面各层的投射神经元是小鼠视觉皮层的显着特征。我们建议模块组织丘脑皮质输入、皮质内处理流和跨丘脑通信,这些通信是不同感觉和感觉运动功能的基础。
更新日期:2023-03-27
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