The beating of motile cilia requires the coordinated action of diverse machineries that include not only the axonemal dynein arms, but also the central apparatus, the radial spokes, and the microtubule inner proteins. These machines exhibit complex radial and proximodistal patterns in mature axonemes, but little is known about the interplay between them during motile ciliogenesis. Here, we describe and quantify the relative rates of axonemal deployment for these diverse cilia beating machineries during the final stages of differentiation of Xenopus epidermal multiciliated cells.

中文翻译：

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在脊椎动物多纤毛细胞生长的轴丝中有序部署不同的纤毛打动机

运动纤毛的跳动需要多种机器的协调作用，这些机器不仅包括轴丝动力蛋白臂，还包括中央装置、径向辐条和微管内部蛋白质。这些机器在成熟轴丝中表现出复杂的径向和近远模式，但人们对它们在运动纤毛发生过程中之间的相互作用知之甚少。在这里，我们描述并量化了爪蟾表皮多纤毛细胞分化的最后阶段这些不同纤毛跳动机制的轴丝部署的相对速率。