Aim: To quantitatively analyze the vascular and structure abnormalities in the papillary areas in eyes with noninfectious uveitis during different periods using optical coherence tomography angiography (OCTA). Methods: Forty eyes of 40 uveitis patients in the acute phase, 12 eyes of 12 patients with inactive uveitis and 21 eyes of 21 healthy controls were included in this study. RPCvd% and pRNFL thickness in different regions were automatically measured and calculated by OCTA. Correlation between RPCvd% and pRNFL was assessed. Results: RPCvd% was significantly higher in uveitis-inactive eyes than in active eyes in the inferior quadrant (p = 0.036), whole image (p = 0.041) and inferior nasal (p = 0.001) sector. The RPCvd% in active uveitis eyes was lower compared to healthy eyes in the inside disc sector (p = 0.026). pRNFL was notably greater in the active group compared to the healthy group. Positive correlations were identified between pRNFL and RPCvd% both in active and inactive uveitis eyes. Conclusions: Compared with active uveitis, papillary microcirculation showed a significant improvement in inactive uveitis eyes (anterior or pan-uveitis). RPCvd% may serve as a sensitive indicator to supervising uveitis progression and treatment response using OCTA.

目的：应用光学相干断层扫描血管造影（OCTA）定量分析不同时期非感染性葡萄膜炎眼乳头区血管结构异常情况。方法：纳入急性期葡萄膜炎患者40例40眼、非活动性葡萄膜炎患者12例12眼和健康对照者21例21眼。不同区域的 RPCvd% 和 pRNFL 厚度由 OCTA 自动测量和计算。评估了 RPCvd% 和 pRNFL 之间的相关性。结果：在下象限 ( p  = 0.036)、整个图像 ( p  = 0.041) 和下鼻腔 ( p = 0.001) 部门。与健康眼睛相比，活动性葡萄膜炎眼睛的 RPCvd% 较低（p  = 0.026）。与健康组相比，pRNFL 在活动组中明显更高。在活动性和非活动性葡萄膜炎眼中，pRNFL 和 RPCvd% 之间存在正相关。结论：与活动性葡萄膜炎相比，乳头微循环在非活动性葡萄膜炎眼（前葡萄膜炎或全葡萄膜炎）中表现出显着改善。RPCvd% 可作为使用 OCTA 监测葡萄膜炎进展和治疗反应的敏感指标。