The synthesis of coumarin derivatives has been an essential topic since its discovery in 1820. In bioactive compounds, the coumarin moiety serves as a backbone, as many such bioactive compounds with the coumarin moiety play a significant role in their bioactivities. Given this moie-ty's relevance, several researchers are developing fused-coumarin derivatives to create new drugs. Mostly the approach done for this purpose was a multicomponent reaction based. Over the years, the multicomponent reaction has gained enormous popularity, and this approach has evolved as a replacement for conventional synthetic methods. Because of all these perspectives, we have reported the various fused-coumarin derivatives synthesized using multicomponent reactions in recent years.

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稠合香豆素衍生物多组分合成研究新进展

自 1820 年发现以来，香豆素衍生物的合成一直是一个重要的课题。在生物活性化合物中，香豆素部分充当主链，因为许多此类具有香豆素部分的生物活性化合物在其生物活性中发挥着重要作用。鉴于该部分的相关性，一些研究人员正在开发稠合香豆素衍生物来创造新药。为此目的所做的方法主要是基于多组分反应。多年来，多组分反应获得了极大的普及，这种方法已经发展成为传统合成方法的替代方法。由于所有这些观点，我们近年来报道了使用多组分反应合成的各种稠合香豆素衍生物。