We determined anti-rubella and anti-measles immunoglobulin G (IgG) in 7- to 19-year-old children and adolescents with vaccine only-induced immunity of Córdoba, Argentina, during a 6-month period over 2021-2022. Of the 180 individuals studied, 92.2% and 88.3% were positive for anti-measles and anti-rubella IgG, respectively. No significant differences were found comparing anti-rubella IgG concentrations (p = 0.144) and anti-measles IgG concentrations (p = 0.105) of individuals classified by age, but anti-measles IgG and anti-rubella IgG levels were significantly higher among female individuals compared with males (p = 0.031 and p = 0.036, respectively). Female subjects in the younger age group had higher concentrations of anti-rubella IgG as well (p = 0.020), even when anti-measles IgG concentrations did not differ among female age-subgroups (p = 0.187). In contrast, age subgroups of male individuals did not have significantly different IgG concentrations for rubella (p = 0.745) or measles (p = 0.124). Among samples with discordant results (22/180, 12.6%), 9.1% were negative for rubella but positive for measles; 13.6% were equivocal for rubella and positive for measles; 22.7% were equivocal for rubella and negative for measles, while 54.5% were positive for rubella but negative for measles. The findings indicate a seroprevalence below recommended for preventing measles in the population studied, while they evidence the need for standardization of serological tests for rubella IgG.

中文翻译：

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阿根廷科尔多瓦儿童和青少年的麻疹和风疹血清流行率：消除计划背景下的横断面研究。

我们在 2021 年至 2022 年 6 个月期间，测定了阿根廷科尔多瓦仅疫苗诱导免疫力的 7 至 19 岁儿童和青少年的抗风疹和抗麻疹免疫球蛋白 G (IgG)。在 180 名研究对象中，分别有 92.2% 和 88.3% 的抗麻疹 IgG 和抗风疹 IgG 呈阳性。按年龄分类的个体的抗风疹 IgG 浓度 (p = 0.144) 和抗麻疹 IgG 浓度 (p = 0.105) 比较，没有发现显着差异，但女性个体的抗麻疹 IgG 和抗风疹 IgG 水平显着较高与男性相比（分别为 p = 0.031 和 p = 0.036）。即使抗麻疹 IgG 浓度在女性年龄亚组之间没有差异 (p = 0.187)，年轻年龄组中的女性受试者也具有较高浓度的抗风疹 IgG (p = 0.020)。相比之下，男性个体的年龄亚组对于风疹 (p = 0.745) 或麻疹 (p = 0.124) 的 IgG 浓度没有显着差异。在结果不一致的样本中（22/180，12.6%），9.1%的风疹呈阴性，但麻疹呈阳性；13.6% 的风疹诊断结果模棱两可，而麻疹诊断结果呈阳性；22.7% 的人对风疹的诊断结果模棱两可，但对麻疹的诊断结果呈阴性，而 54.5% 的人对风疹的诊断结果呈阳性，但对麻疹的结果呈阴性。研究结果表明，所研究人群的血清阳性率低于预防麻疹的推荐值，同时也证明了风疹 IgG 血清学检测标准化的必要性。