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Antithrombotic treatment strategies in patients with established coronary atherosclerotic disease.
European Heart Journal-Cardiovascular Pharmacotherapy ( IF 7.1 ) Pub Date : 2023-07-29 , DOI: 10.1093/ehjcvp/pvad032
Marco Valgimigli 1, 2 , Victor Aboyans 3 , Dominick Angiolillo 4 , Dan Atar 5 , Davide Capodanno 6 , Sigrun Halvorsen 7, 8 , Stefan James 9 , Peter Jüni 10 , Vijay Kunadian 11 , Antonio Landi 1, 2 , Sergio Leonardi 12 , Roxana Mehran 13 , Gilles Montalescot 14 , Eliano Pio Navarese 15 , Josef Niebauer 16 , Angelo Oliva 17 , Raffaele Piccolo 18 , Susanna Price 19 , Robert F Storey 20 , Heinz Völler 21 , Pascal Vranckx 22, 23 , Stephan Windecker 24 , Keith A A Fox 25
Affiliation  

Multiple guidelines and consensus papers have addressed the role of antithrombotic strategies in patients with established coronary artery disease (CAD). Since evidence and terminology continue to evolve, the authors undertook a consensus initiative to guide clinicians to select the optimal antithrombotic regimen for each patient. The aim of this document is to provide an update for clinicians on best antithrombotic strategies in patients with established CAD, classifying each treatment option in relation to the number of antithrombotic drugs irrespective of whether the traditional mechanism of action is expected to mainly inhibit platelets or coagulation cascade. With the aim to reach comprehensiveness of available evidence, we systematically reviewed and performed meta-analyses by means of both direct and indirect comparisons to inform the present consensus document.

中文翻译:

已确诊冠状动脉粥样硬化性疾病患者的抗血栓治疗策略。

多个指南和共识文件讨论了抗血栓策略在确诊冠状动脉疾病 (CAD) 患者中的作用。由于证据和术语不断发展,作者采取了一项共识倡议,指导临床医生为每位患者选择最佳的抗血栓治疗方案。本文件的目的是为临床医生提供有关已确诊 CAD 患者最佳抗血栓策略的最新信息,根据抗血栓药物的数量对每种治疗方案进行分类,无论传统的作用机制是否主要抑制血小板或凝血级联。为了达到现有证据的全面性,我们通过直接和间接比较的方式系统地审查和进行荟萃分析,以为本共识文件提供信息。
更新日期:2023-04-29
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