Transition metals catalyzed C-H bond activation reactions have appeared as an emerging field to introduce different functional groups in the inactivated saturated and unsaturated C-H bonds. C-S and C-Se bond constructions in aromatic scaffolds are very interesting due to the important applications of organochalcogen reagents in pharmaceutical chemistry and the material world. The introduction of sulphur or selenium moiety to an inert C-H functionality of an arene under transition metal catalysis has become one of the prime challenges and targets in recent years. In this perspective, various transition metals such as Cu, Ni, Co, Pd, Rh, Ru etc. have been extensively studied. Aromatic arenes owning bearing suitable directing groups appeared as the most promising coupling partners to selectively synthesize differently substituted aryl sulfones and aryl sulfides/selenides. The synthetic strategies were highly convenient owing to the regioselectivity of products, broad substrate scope, mild reaction conditions and excellent functional group tolerance. The current review article comprehensively summarizes the extent of C-S/Se bond formation via transition metal-catalyzed C-H bond activation with the assistance of directing groups to govern the site selectivity.

中文翻译：

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过渡金属催化芳烃和杂芳烃的直接 CH 硫属化反应

过渡金属催化的CH键活化反应已成为一个新兴领域，在失活的饱和和不饱和CH键中引入不同的官能团。由于有机硫属试剂在药物化学和材料领域的重要应用，芳香族支架中的 CS 和 C-Se 键结构非常有趣。在过渡金属催化下将硫或硒部分引入芳烃的惰性CH官能团已成为近年来的主要挑战和目标之一。从这个角度来看，各种过渡金属如Cu、Ni、Co、Pd、Rh、Ru等得到了广泛的研究。具有合适导向基团的芳香芳烃似乎是选择性合成不同取代的芳基砜和芳基硫醚/硒化物的最有前途的偶联伙伴。由于产物的区域选择性、底物范围广、反应条件温和以及优异的官能团耐受性，该合成策略非常方便。当前的综述文章全面总结了通过过渡金属催化的 CH 键活化在引导基团控制位点选择性的帮助下形成 CS/Se 键的程度。