We read with interest the article by Hazan and colleagues “Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity”1 in which they reported a significant decrement in gut bifidobacteria in persons with severe Covid. This caught our attention because the common artificial sweetener sucralose (eg, Splenda) has a profound effect on the microbiome including significant reductions in bifidobacteria in the gut. Abou-Donia et al 2 administered sucralose to rats (delivered in Splenda) for 12 weeks at dosages approved for human use in the United States …

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严重的 SARS-CoV-2 感染：人造甜味剂三氯蔗糖起作用了吗？

我们感兴趣地阅读了 Hazan 及其同事的文章“COVID-19 微生物丢失：双歧杆菌、粪杆菌耗竭和微生物组多样性降低与 SARS-CoV-2 感染严重程度相关”1，他们在文中报告患有 SARS-CoV-2 感染的人肠道双歧杆菌显着减少严重的Covid。这引起了我们的注意，因为常见的人造甜味剂三氯蔗糖（例如，Splenda）对微生物组具有深远的影响，包括肠道中双歧杆菌的显着减少。Abou-Donia 等人 2 以美国批准的人用剂量向大鼠（在 Splenda 中递送）施用三氯蔗糖 12 周……