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One-dimensional photonic crystal-based biosensor for the detection of glucose concentration in human urine
Journal of Nanophotonics ( IF 1.5 ) Pub Date : 2023-05-01 , DOI: 10.1117/1.jnp.17.026007
Abdelkarim El Mouncharih 1 , Rabi Takassa 1 , Omar Farkad 1 , Abdelaziz Tchenka 1 , Fatima Elfatouaki 1 , El Alami Ibnouelghazi 1 , Driss Abouelaoualim 1
Affiliation  

A biosensor structure based on a ternary photonic crystal (TPC) containing a defect is designed and simulated. This proposed biosensor detects the concentration of glucose in human urine. Based on the transfer matrix method, we theoretically studied the transmission spectra through the TPC presuming blood samples with different refractive indices (RIs) infiltrated into the defect layer of the proposed structures. By varying the concentration of glucose in the urine, the RI of the urine is changed, which in turn changes the sensor’s output response; both transmission response and resonance wavelength are affected. We evaluated average sensitivity (S) for the number of periods at different values N for optimization purposes. Our results show that the biosensor has performance parameters for a period value N = 6. Indeed, a value of 1033 nm of full width at half maximum photonic bandgap can be observed with a S of 965 nm / RIU. The quality factor is 1892.542 and the figure of merit is 756.86 RIU − 1. The proposed biosensor can be a miniaturized structure with extreme sensitivity in the concentration of glucose detection models

中文翻译:

基于一维光子晶体的生物传感器用于检测人尿液中的葡萄糖浓度

设计并模拟了一种基于包含缺陷的三元光子晶体 (TPC) 的生物传感器结构。这种拟议的生物传感器检测人体尿液中的葡萄糖浓度。基于传递矩阵方法,我们从理论上研究了通过 TPC 的透射光谱,假设具有不同折射率 (RI) 的血液样本渗透到所提出结构的缺陷层中。通过改变尿液中的葡萄糖浓度,改变尿液的折射率,进而改变传感器的输出响应;传输响应和共振波长都会受到影响。为了优化目的,我们评估了不同值 N 下的周期数的平均灵敏度 (S)。我们的结果表明,生物传感器具有周期值 N = 6 的性能参数。确实,使用 965 nm / RIU 的 S 可以观察到 1033 nm 的半峰全宽光子带隙值。品质因数为 1892.542,品质因数为 756.86 RIU - 1。所提出的生物传感器可以是微型结构,在葡萄糖浓度检测模型中具有极高的灵敏度
更新日期:2023-05-01
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