Abstract

Depression and anxiety are related to physical activity among people with chronic obstructive pulmonary disease (COPD), although the strength and direction of the reported relationships are inconsistent. This study systematically synthesized the relationships between physical activity and i) depression and ii) anxiety in people with COPD. Physical activity measurement type (objective, self-report) was examined as a moderator of these relationships. A systematic search of physical activity and COPD was conducted from inception to February 2022 across 8 databases. Studies were included if they provided correlation coefficients for the relationship between measures of physical activity and depression or anxiety in people with COPD and were published in English. Two reviewers independently screened, reviewed and extracted data, with discrepancies resolved by a third reviewer. Across 13 studies, a small relationship was found between physical activity and depression, weighted r = −0.15, 95%CI [-0.21, −0.10], which was not moderated by physical activity measurement type. Across 8 studies, a negligible relationship was found between physical activity and anxiety, weighted r = −0.03, 95%CI [-0.11, 0.04], although this was moderated by physical activity measurement type, such that self-reported physical activity had a small negative relationship with anxiety (weighted r = −0.09, 95% CI [-0.15, −0.03]) and objectively measured physical activity had a small positive relationship (weighted r = 0.07, 95% CI [-0.13, 0.26]). In COPD, the bivariate association between physical activity and anxiety and depression are small.

摘要

抑郁和焦虑与慢性阻塞性肺疾病（COPD）患者的身体活动有关，尽管所报道的关系的强度和方向不一致。这项研究系统地综合了慢性阻塞性肺病患者的体力活动与 i) 抑郁和 ii) 焦虑之间的关系。身体活动测量类型（客观、自我报告）被检查为这些关系的调节因素。从成立到 2022 年 2 月，我们在 8 个数据库中对体力活动和慢性阻塞性肺病进行了系统检索。如果研究提供了慢性阻塞性肺病患者体力活动测量与抑郁或焦虑之间关系的相关系数，并且以英文发表，则研究被纳入。两名评审员独立筛选、评审和提取数据，差异由第三位评审员解决。在 13 项研究中，发现体力活动与抑郁之间存在微小关系，加权r  = −0.15, 95%CI [-0.21, −0.10]，不受身体活动测量类型的调节。在 8 项研究中，发现体力活动与焦虑之间的关系可以忽略不计，加权r  = -0.03，95%CI [-0.11, 0.04]，尽管这种关系受到体力活动测量类型的调节，因此自我报告的体力活动具有与焦虑之间存在较小的负相关关系（加权r  = -0.09，95% CI [-0.15，-0.03]），而客观测量的体力活动则存在较小的正相关关系（加权r  = 0.07，95% CI [-0.13，0.26]）。在慢性阻塞性肺病中，体力活动与焦虑和抑郁之间的二元关联很小。