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Association of Heart Transplant Volume with Presence of Lung Transplant Programs and Heart Transplant’s SRTR One-year Survival Rating
The Thoracic and Cardiovascular Surgeon ( IF 1.5 ) Pub Date : 2023-07-15 , DOI: 10.1055/a-2095-6636
Jake L Rosen 1 , Danial Ahmad 1 , Anjali Uphadyaya 1 , Andrew T Brodie 2 , Gabriel Gaw 1, 3 , Indranee Rajapreyar 1 , J Eduardo Rame 1 , Rene J Alvarez 1 , Keshava Rajagopal 1 , John W Entwistle 1 , Howard T Massey 1 , Vakhtang Tchantchaleishvili 1
Affiliation  

Background Several factors affect heart transplant (HTx) and lung transplant (LTx) program outcomes. Variabilities in institutional and community characteristics have been shown to influence survival. At present, half of HTx centers in the United States do not possess a concomitant LTx program. This study sought to better understand the characteristics of HTx with and without LTx programs.

Methods Nationwide transplant data were collected from the Scientific Registry of Transplant Recipients (SRTR) in August 2020. SRTR star rating ranges from tier 1 (lowest) to tier 5 (highest). HTx volumes and SRTR star ratings for survival were compared between the centers with heart-only (H0) programs and the centers with heart-lung (HL) programs.

Results SRTR star ratings were available for 117 transplant centers with one or more HTx reported. The median number of HTx performed over 1 year was 16 (interquartile range [IQR]: 2–29). The number of HL centers (n = 67, 57.3%) were comparable to H0 centers (n = 50, 42.7%; p = 0.14). The HTx volume at the HL centers (28 [IQR: 17–41]) exceeded the HTx volume at the H0 centers (13 [IQR: 9–23]; p < 0.01), but were comparable to the LTx volume at the HL centers (31 [IQR: 16–46]; p = 0.25). The median HTx one-year survival rating was 3 (IQR: 2–4) at both the H0 and HL centers (p = 0.85). The HTx and LTx volumes were positively associated with the respective 1-year survivals (p < 0.01).

Conclusion While the presence of an LTx program is not directly associated with HTx survival, it has a positive association with the HTx volume. The HTx and LTx volumes are positively associated with the 1-year survival.



中文翻译:

心脏移植量与肺移植计划的存在以及心脏移植的 SRTR 一年生存率之间的关系

背景 有几个因素会影响心脏移植 (HTx) 和肺移植 (LTx) 计划的结果。制度和社区特征的差异已被证明会影响生存。目前,美国一半的 HTx 中心没有配套的 LTx 计划。本研究旨在更好地了解有和没有 LTx 程序的 HTx 的特征。

方法 2020 年 8 月从移植受者科学登记处 (SRTR) 收集全国移植数据。SRTR 星级评分范围从 1 级(最低)到 5 级(最高)。对仅开展心脏 (H0) 项目的中心和开展心肺 (HL) 项目的中心之间的 HTx 体积和 SRTR 生存星级进行了比较。

结果 117 个报告了一种或多种 HTx 的移植中心获得了 SRTR 星级评级。一年内进行的 HTx 中位数为 16 次(四分位距 [IQR]:2-29)。HL 中心的数量 ( n = 67, 57.3%) 与 H0 中心的数量 ( n  = 50, 42.7%; p  = 0.14) 相当。HL 中心的 HTx 体积 (28 [IQR: 17–41]) 超过 H0 中心的 HTx 体积 (13 [IQR: 9–23];p  < 0.01),但与 HL 的 LTx 体积相当中心(31 [IQR:16–46];p  = 0.25)。H0 和 HL 中心的 HTx 一年生存率中位数均为 3(IQR:2-4)(p = 0.85)。HTx 和 LTx 体积与各自的 1 年生存率呈正相关 ( p  < 0.01)。

结论 虽然 LTx 计划的存在与 HTx 存活率没有直接关系,但它与 HTx 体积呈正相关。HTx 和 LTx 体积与 1 年生存率呈正相关。

更新日期:2023-07-16
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