OBJECTIVE To evaluate the effect of virtual group music therapy on apathy in people with Parkinson's disease (PD). INTRODUCTION Apathy affects 40% of people with PD, lacks effective therapies, and independently predicts poorer quality of life and greater caregiver burden. Music therapy is the clinical application of music to address a person's physical or emotional needs and is effective in treating apathy in dementia. METHODS People with idiopathic PD and apathy (Movement Disorders Society-Unified Parkinson's Disease Rating Scale, apathy item ≥ 2) and their caregivers participated in twelve, weekly virtual group music therapy sessions, with session attendance signifying adherence. Participants completed pre- and post-intervention assessments of apathy (Apathy Scale (AS)), quality of life (Parkinson's Disease Questionnaire-short form), functional ability (Schwab & England Activities of Daily Living Scale), depression (Beck Depression Inventory (BDI-II)), and cognition (Montreal Cognitive Assessment-Blind). Among secondary outcomes, we assessed caregiver burden (Zarit Burden Interview-short form) and strain (Multidimensional Caregiver Strain Index). RESULTS Sixteen PD participants (93.8% men, mean age 68.3 ± 8.4 years, median 6 years PD duration) and their caregivers (93.8% women, mean age 62.6 ± 11 years) completed the study. All PD participants and 88% of caregivers were >70% adherent to the intervention. Apathy (AS, effect size = 0.767, P = 0.002) and depression (BDI-II, effect size = 0.542, P = 0.03) improved, with no change in caregiver measures. CONCLUSION Group music therapy is an effective treatment for apathy in PD and may improve mood. The virtual format is a feasible alternative to in-person sessions with high adherence and satisfaction.

中文翻译：

---

虚拟团体音乐治疗帕金森病冷漠症：一项试点研究。

目的 评估虚拟团体音乐疗法对帕金森病 (PD) 患者冷漠的影响。简介 冷漠影响 40% 的帕金森病患者，缺乏有效的治疗方法，并独立预测生活质量较差和护理人员负担更大。音乐疗法是临床应用音乐来满足一个人的身体或情感需求，可有效治疗痴呆症的冷漠。方法 特发性帕金森病和冷漠患者（运动障碍协会-统一帕金森病评定量表，冷漠项目≥2）及其护理人员参加了 12 次每周一次的虚拟团体音乐治疗课程，参加会议表明坚持治疗。参与者完成干预前和干预后的冷漠评估（冷漠量表（AS））、生活质量（帕金森病问卷简表）、功能能力（施瓦布和英格兰日常生活活动量表）、抑郁（贝克抑郁量表（贝克抑郁量表） BDI-II)) 和认知（蒙特利尔认知评估-盲法）。在次要结果中，我们评估了看护者负担（Zarit Burden Interview-short form）和压力（多维看护者压力指数）。结果 16 名 PD 参与者（93.8% 为男性，平均年龄 68.3 ± 8.4 岁，PD 持续时间中位数为 6 年）及其照顾者（93.8% 为女性，平均年龄 62.6 ± 11 岁）完成了研究。所有 PD 参与者和 88% 的护理人员对干预的依从性均超过 70%。冷漠（AS，效应大小 = 0.767，P = 0.002）和抑郁（BDI-II，效应大小 = 0.542，P = 0.03）有所改善，但护理措施没有变化。结论 团体音乐疗法是治疗帕金森病冷漠的有效方法，并且可以改善情绪。虚拟形式是面对面会议的可行替代方案，具有很高的依从性和满意度。