BACKGROUND Insulin Resistance (IR) are associated with Hypertension (HTN). Triglyceride glucose-body mass index (TyG-BMI) is a readily available and clinically significant indicator of IR. This study aimed to investigate whether TyG-BMI is independently associated with HTN. METHODS A total of 15,464 patients with normal blood glucose from 2004 to 2016 participated in this study. Participants were divided into four groups using the quartile method: TyG-BMI below 153.1, between 153.1 and 174.2, between 174.2 and 199.3, and over 199.3. The covariates included age, sex, BMI, WC, HDL-C, TC, TG, HbA1c, FPG, ALT, AST, GGT, SBP, DBP, smoking status, alcohol consumption, and exercise habits. RESULTS The average age was 43.7 ± 8.9 years, and 45.4% were men. The prevalence of HTN was 6.2% (964/15464) of the population. TyG-BMI remained significantly associated with HTN after multivariate adjustment for TyG-BMI as a continuous variable (adjusted OR = 2.87, 95% CI: 1.90-4.34). Each 10-unit rise in TyG-BMI (continuous variable) was linked to a 31% increase in the prevalence of HTN (adjusted OR = 1.31, 95% CI: 1.25-1.37). In the subgroup analysis stratified by age, sex, waist circumference, and smoking status, the association between TyG-BMI and HTN were stable. CONCLUSION In this study, TyG-BMI was highly correlated with HTN, but more experiments and different populations are needed to verify this.

中文翻译：

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日本正常血糖受试者的 TyG-BMI 和高血压：一项横断面研究。

背景技术胰岛素抵抗(IR)与高血压(HTN)相关。甘油三酯葡萄糖体重指数 (TyG-BMI) 是一种容易获得且具有临床意义的 IR 指标。本研究旨在探讨 TyG-BMI 是否与 HTN 独立相关。方法 2004年至2016年共15 464例血糖正常患者参与本研究。使用四分位法将参与者分为四组：TyG-BMI低于153.1、153.1至174.2之间、174.2至199.3之间以及199.3以上。协变量包括年龄、性别、BMI、WC、HDL-C、TC、TG、HbA1c、FPG、ALT、AST、GGT、SBP、DBP、吸烟状况、饮酒和运动习惯。结果 平均年龄为 43.7 ± 8.9 岁，其中 45.4% 为男性。人群中高血压患病率为 6.2% (964/15464)。将 TyG-BMI 作为连续变量进行多变量调整后，TyG-BMI 仍与 HTN 显着相关（调整后 OR = 2.87，95% CI：1.90-4.34）。TyG-BMI（连续变量）每上升 10 个单位，HTN 患病率就会增加 31%（调整后 OR = 1.31，95% CI：1.25-1.37）。在按年龄、性别、腰围和吸烟状况分层的亚组分析中，TyG-BMI 和 HTN 之间的相关性稳定。结论本研究中TyG-BMI与HTN高度相关，但还需要更多的实验和不同人群来验证。在按年龄、性别、腰围和吸烟状况分层的亚组分析中，TyG-BMI 和 HTN 之间的相关性稳定。结论本研究中TyG-BMI与HTN高度相关，但还需要更多的实验和不同人群来验证。在按年龄、性别、腰围和吸烟状况分层的亚组分析中，TyG-BMI 和 HTN 之间的相关性稳定。结论本研究中TyG-BMI与HTN高度相关，但还需要更多的实验和不同人群来验证。