MicroRNAs (miRNAs), a type of non-coding RNA, have been demonstrated to be essential posttranscriptional modulators in oral diseases and inflammatory responses. However, the specific role of miR-27a-5p in periodontitis requires further investigation. In this study, we used both cellular and animal models to determine how miR-27a-5p affects the pathogenesis of periodontitis and its associated biological functions.

中文翻译：

---

miR-27a-5p通过靶向十号染色体上缺失的磷酸酶和张力蛋白同源物减轻牙周炎症

MicroRNA (miRNA) 是一种非编码 RNA，已被证明是口腔疾病和炎症反应中重要的转录后调节剂。然而，miR-27a-5p在牙周炎中的具体作用还需要进一步研究。在这项研究中，我们使用细胞和动物模型来确定 miR-27a-5p 如何影响牙周炎的发病机制及其相关的生物学功能。