With its critical role in human health and disease, the microbiome has transformed modern biology. Over the past few years, microbiome research has evolved rapidly, with microbiologists gradually shifting their focus from cataloging microorganisms in the human microbiome to understanding their functional roles and how they interact with the host. Here, we present the global trends in microbiome research and summarize the past and current work on microbiome published in Protein & Cell. In closing, we highlight some of the major advancements in microbiome research, including technical, practical, and conceptual advancements, that aim to enhance disease diagnosis, medicine development, and personalized interventions.

中文翻译：

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微生物组研究展望：过去、现在和未来。

微生物组在人类健康和疾病中发挥着至关重要的作用，已经改变了现代生物学。在过去的几年里，微生物组研究发展迅速，微生物学家逐渐将重点从对人类微生物组中的微生物进行编目转向了解它们的功能作用以及它们如何与宿主相互作用。在这里，我们介绍了微生物组研究的全球趋势，并总结了《Protein & Cell》上发表的过去和当前的微生物组工作。最后，我们强调微生物组研究的一些重大进展，包括技术、实践和概念方面的进步，旨在加强疾病诊断、药物开发和个性化干预。