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Topographic consideration on the occurrence of ipsilesional facial paresis in lateral medullary infarction.
Cerebrovascular Diseases ( IF 2.9 ) Pub Date : 2023-05-10 , DOI: 10.1159/000530986
Yong Kyun Kim 1 , Yong Bum Kim 2 , Bum Chun Suh 2 , Yun Hyeong Jeong 2 , Soei Ann 2 , Pil Wook Chung 2
Affiliation  

INTRODUCTION The purpose of this study was to identify course of corticobulbar tract and factors associated with the occurrence of facial paresis (FP) in lateral medullary infarction (LMI). METHODS Patients diagnosed with LMI who were admitted totertiary hospital were retrospectively investigated and divided into two groups based on the presence of FP. FP was defined as grade II or more by the House-Brackmann scale. Differences between the two groups were analyzed with respect to Anatomical location of the lesions, demographic data (age, sex), risk factors (diabetes, hypertension, smoking, prior stroke, atrial fibrillation and other cardiologic factors), large vessel involvement on magnetic resonance angiography, other symptoms and signs (sensory symptom, gait ataxia, limb ataxia, dizziness, Horner syndrome, hoarseness, dysphagia, dysarthria, nystagmus, nausea/vomiting, headache, neck pain, diplopia and hiccup). RESULTS Among 44 LMI patients, 15 patients (34%) had FP, and all of them had ipsilesional central type FP. The FP group tended to involve upper (p < 0.0001) and relative ventral (p = 0.019) part of lateral medulla. Horizontally large lesion was also related to the presence of FP (p = 0.044). Dysphagia (p = 0.001), dysarthria (p = 0.003) and hiccup (p = 0.034) were more likely to be accompanied by FP. Otherwise, there were no significant differences. CONCLUSION The results of present study indicate that the corticobulbar fibers innervating lower face decussate at the upper level of medulla and ascend through the dorsolateral medulla where the concentration of the fibers is densest near the nucleus ambiguus.

中文翻译:

延髓外侧梗死同侧面瘫发生的地形学考虑。

简介 本研究的目的是确定皮质延髓束的病程以及与延髓外侧梗塞 (LMI) 中面瘫 (FP) 发生相关的因素。方法对三级医院确诊为LMI的患者进行回顾性调查,根据是否有FP分为两组。House-Brackmann 量表将 FP 定义为 II 级或更高级别。分析了两组之间的差异,包括病变的解剖位置、人口统计数据(年龄、性别)、危险因素(糖尿病、高血压、吸烟、既往中风、心房颤动和其他心脏病因素)、大血管受累磁共振血管造影、其他症状和体征(感觉症状、步态共济失调、肢体共济失调、头晕、霍纳综合征、声音嘶哑、吞咽困难、构音障碍、眼球震颤、恶心/呕吐、头痛、颈部疼痛、复视和打嗝)。结果 44例LMI患者中,15例(34%)FP,均为同侧中央型FP。FP 组倾向于涉及外侧髓质的上部 (p < 0.0001) 和相对腹侧 (p = 0.019) 部分。横向较大的病变也与 FP 的存在有关 (p = 0.044)。吞咽困难 (p = 0.001)、构音障碍 (p = 0.003) 和打嗝 (p = 0.034) 更可能伴有 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。结果 44例LMI患者中,15例(34%)FP,均为同侧中央型FP。FP 组倾向于涉及外侧髓质的上部 (p < 0.0001) 和相对腹侧 (p = 0.019) 部分。横向较大的病变也与 FP 的存在有关 (p = 0.044)。吞咽困难 (p = 0.001)、构音障碍 (p = 0.003) 和打嗝 (p = 0.034) 更可能伴有 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。结果 44例LMI患者中,15例(34%)FP,均为同侧中央型FP。FP 组倾向于涉及外侧髓质的上部 (p < 0.0001) 和相对腹侧 (p = 0.019) 部分。横向较大的病变也与 FP 的存在有关 (p = 0.044)。吞咽困难 (p = 0.001)、构音障碍 (p = 0.003) 和打嗝 (p = 0.034) 更可能伴有 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。FP 组倾向于涉及外侧髓质的上部 (p < 0.0001) 和相对腹侧 (p = 0.019) 部分。横向较大的病变也与 FP 的存在有关 (p = 0.044)。吞咽困难 (p = 0.001)、构音障碍 (p = 0.003) 和打嗝 (p = 0.034) 更可能伴有 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。FP 组倾向于涉及外侧髓质的上部 (p < 0.0001) 和相对腹侧 (p = 0.019) 部分。横向较大的病变也与 FP 的存在有关 (p = 0.044)。吞咽困难 (p = 0.001)、构音障碍 (p = 0.003) 和打嗝 (p = 0.034) 更可能伴有 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。034) 更有可能伴随着 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。034) 更有可能伴随着 FP。否则,没有显着差异。结论 本研究的结果表明,支配下面部的皮质延髓纤维在髓质上层交叉交叉并通过背外侧髓质上行,其中纤维在疑核附近最密集。
更新日期:2023-05-10
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