Metabolomics, an emerging omics technology developed in the post-gene age, is an important part of systems biology. It interprets the pathophysiological state of the subject by quantitatively describing the dynamic changes of metabolites through analytical methods, mainly mass spectrometry (MS) and nuclear magnetic resonance (NMR). Assisted reproductive technology (ART) is a method used to manipulate sperm, oocytes, and embryos to achieve conception. Recently, several studies have reported that metabolomics methods can be used to measure metabolites in ART samples; these metabolites can be used to evaluate the quality of gametes and embryos. This article reviews the progress of research on metabolomics and the application of this technology in the field of ART, thus providing a reference for research and development directions in the future.

中文翻译：

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代谢组学及其在辅助生殖技术中的应用。

代谢组学是后基因时代发展起来的新兴组学技术，是系统生物学的重要组成部分。它通过分析方法，主要是质谱（MS）和核磁共振（NMR），定量描述代谢物的动态变化，从而解释受试者的病理生理状态。辅助生殖技术（ART）是一种用于操纵精子、卵母细胞和胚胎以实现受孕的方法。最近，一些研究报道代谢组学方法可用于测量 ART 样品中的代谢物；这些代谢物可用于评估配子和胚胎的质量。本文综述了代谢组学的研究进展以及该技术在ART领域的应用，为未来的研究和发展方向提供参考。