Knowledge, attitudes, and practices (KAP) surveys on malaria and antimalarial mass drug administration (MDA) have not received much attention in the Union of the Comoros. This study is a household-based cross-sectional survey using a multi-stage sampling technique aiming at investigating KAP toward malaria and antimalarial MDA with artemisinin-piperaquine among heads of households on Grande Comore Island, the largest island of the Comoros. A predefined structured questionnaire containing socio-demographic characteristics and questions about malaria and antimalarial MDA was administered to 1,368 randomly selected heads of households from 10 malaria-endemic villages on Grande Comore Island. The results showed that 81.4% of the heads of households knew that malaria is a transmissible disease, 77.6% recognized mosquitoes as the vectors of malaria, and 70.8% recognized fever as one of the frequent symptoms of malaria; 40.8% of respondents remembered the name of the antimalarial drug used for MDA, and 62.1% remembered the color of the antimalarial tablets; and 65.1% chose to go to a public health center to seek treatment as their first option within 24 hr of the onset of initial malaria symptoms. This study found that most heads of households had a reasonable level of knowledge about malaria and antimalarial MDA. However, only 7.3% obtained full points on all knowledge-related questions. Misconceptions about malaria cause, transmission, diagnostic method, and antimalarial MDA exist in the community of Grande Comore Island. As the Comoros continues to put great efforts to go toward malaria elimination, the community's KAP on malaria and antimalarial MDA is crucial to guarantee the community's long-term adherence to malaria elimination interventions and could become key to guaranteeing malarial elimination in the Comoros. Therefore, there is a great need to improve malaria prevention awareness through strengthening malaria education and promoting behavioral change. Heads of households should be the core target of malaria education and behavioral change for malaria elimination.

关于疟疾和抗疟疾大规模药物管理 (MDA) 的知识、态度和实践 (KAP) 调查在科摩罗联盟并未受到太多关注。本研究是一项基于家庭的横断面调查，采用多阶段抽样技术，旨在调查科摩罗最大岛屿大科摩罗岛的户主对疟疾和使用青蒿素-哌喹的抗疟疾 MDA 的 KAP。对来自格兰德科摩罗岛 10 个疟疾流行村庄的 1,368 名随机选择的户主进行了预定义的结构化问卷调查，其中包含社会人口统计学特征以及有关疟疾和抗疟药 MDA 的问题。结果显示，81.4%的户主知道疟疾是一种传染性疾病，77.6%的户主认为蚊子是疟疾的传播媒介，70.8% 的人认为发烧是疟疾的常见症状之一；40.8%的受访者记得MDA所用抗疟药的名称，62.1%记得抗疟药片的颜色；65.1% 的人在出现最初的疟疾症状后 24 小时内选择去公共卫生中心寻求治疗作为他们的第一选择。这项研究发现，大多数户主对疟疾和抗疟药 MDA 的了解程度合理。然而，只有 7.3% 的人在所有与知识相关的问题上都获得了满分。大科摩罗岛社区存在对疟疾病因、传播、诊断方法和抗疟药 MDA 的误解。随着科摩罗继续努力消除疟疾，社区' s 关于疟疾和抗疟药 MDA 的 KAP 对于保证社区长期坚持消除疟疾干预措施至关重要，并且可能成为保证科摩罗消除疟疾的关键。因此，非常需要通过加强疟疾教育和促进行为改变来提高疟疾预防意识。户主应该是消除疟疾的疟疾教育和行为改变的核心目标。