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Vitamin D is a potential treatment for the management of gastrointestinal mucositis.
Current Opinion in Supportive and Palliative Care ( IF 2.1 ) Pub Date : 2023-06-06 , DOI: 10.1097/spc.0000000000000651
Fizza Munem 1 , Phir C K Thianhlun , Paul H Anderson , Andrea M Stringer
Affiliation  

Gastrointestinal mucositis (GM) is a severe side effect of cancer treatments, negatively impacting the patient's quality of life, and has limited treatment. GM consists of complex biological processes involving apoptosis and inflammation, leading to damage and ulceration of the gastrointestinal system. Recently, vitamin D has been shown to have multiple roles in the gut, including immunomodulation, epithelial barrier regulation and microbiome regulation. Hence, this review aims to put forth vitamin D as a potential therapeutic due to its protective role in the intestine.

中文翻译:

维生素 D 是治疗胃肠道粘膜炎的潜在疗法。

胃肠粘膜炎 (GM) 是癌症治疗的严重副作用,对患者的生活质量产生负面影响,且治疗有限。GM 由涉及细胞凋亡和炎症的复杂生物过程组成,导致胃肠系统损伤和溃疡。最近,维生素 D 已被证明在肠道中具有多种作用,包括免疫调节、上皮屏障调节和微生物组调节。因此,本综述旨在提出维生素 D 由于其对肠道的保护作用而成为一种潜在的治疗方法。
更新日期:2023-06-06
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