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Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns.
Neonatology ( IF 2.5 ) Pub Date : 2023-06-07 , DOI: 10.1159/000529842
Anton Friis Mariager 1, 2 , Alberte Hammeken 3 , Mikkel Malham 1 , Anna Axelsson Raja 4 , Anna Sellmer 5, 6 , Signe Levring Skjellerup 7 , Raheel Altaf Raja 8 , Johan Navne 9 , Anne-Sophie Sillesen 2, 3 , Niels Vejlstrup 4 , Henning Bundgaard 3, 10 , Kasper Karmark Iversen 2, 3 , Ester Garne 11 , Dorthe Lisbeth Jeppesen 1, 3
Affiliation  

BACKGROUND The ductus arteriosus is part of the fetal circulation. Normally, the vessel closes during the cardiac transition. Delayed closure is associated with complications. The aim of this study was to evaluate the age-related prevalence of open ductus arteriosus in full-term neonates. METHODS Echocardiograms were collected in the population study, the Copenhagen Baby Heart Study. The present study included full-term neonates with an echocardiogram performed within 28 days after birth. All echocardiograms were reviewed to assess ductus arteriosus patency. RESULTS A total of 21,649 neonates were included. In neonates examined at day zero and day seven, an open ductus arteriosus was found in 36% and 0.6%, respectively. Beyond day seven, the prevalence remained stable at 0.6%. CONCLUSION More than one-third of full-term neonates had an open ductus arteriosus on the first day of life, declining rapidly within the first week and stabilizing below 1% after day seven.

中文翻译:

足月新生儿中开放性动脉导管的患病率与年龄相关。

背景技术动脉导管是胎儿循环的一部分。通常,血管在心脏转变过程中关闭。延迟闭合与并发症相关。本研究的目的是评估足月新生儿动脉导管开放的年龄相关患病率。方法 在人口研究“哥本哈根婴儿心脏研究”中收集超声心动图。本研究纳入了足月新生儿,并在出生后 28 天内进行了超声心动图检查。检查所有超声心动图以评估动脉导管的通畅性。结果 总共纳入了 21,649 名新生儿。在第 0 天和第 7 天检查的新生儿中,分别有 36% 和 0.6% 发现动脉导管开放。第七天之后,患病率稳定在 0.6%。结论 超过三分之一的足月新生儿在出生第一天动脉导管开放,第一周内动脉导管开放,并在第七天后稳定在 1% 以下。
更新日期:2023-06-07
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