BACKGROUND AND PURPOSE Lateropulsion (LP) is a profound disorder of postural control that has a significant impact on neurorehabilitation. Knowledge of relevant brain areas could guide decisions on appropriate intervention methods. Although LP severity and duration are highly variable in individuals with LP, imaging studies on LP have not sufficiently considered these aspects. The aim of this study was to investigate the lesion location in individuals after stroke and the correlation with LP duration and severity. METHODS A retrospective case-control study using voxel lesion symptom mapping (VLSM) in 74 individuals with right-sided brain lesion (49 with and 25 without LP) was performed to analyze the correlation between lesion location and LP severity. Duration was investigated in a subsample of 22 individuals with LP. LP was diagnosed by means of the Scale for Contraversive Pushing. RESULTS Individuals with LP showed significantly larger lesion sizes compared with the individuals with no LP. VLSM analysis of LP severity did not reveal statistically significant results. VLSM analysis showed a statistically significant association with longer LP duration for the inferior frontal gyrus, the hippocampus, the inferior parietal gyrus, the supramarginal gyrus, the angular gyrus, the temporal cortex, the sagittal stratum, and the superior longitudinal fasciculus. DISCUSSION AND CONCLUSION LP-relevant areas are located in the multisensory network. Areas of the frontoparietal network, which are related to spatial cognition, memory, and attention, were found to be relevant for duration and severity. The findings, especially those regarding duration involving the middle temporal cortex, could explain the better intervention outcomes for methods based more on implicit than on explicit knowledge of verticality.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A433).

中文翻译：

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右侧中风的 Lateropulsion：严重程度和持续时间的大脑解剖相关性。

背景和目的 Lateropulsion (LP) 是一种严重的姿势控制障碍，对神经康复有重大影响。相关大脑区域的知识可以指导对适当干预方法的决策。尽管 LP 严重程度和持续时间在 LP 个体中变化很大，但 LP 的影像学研究并未充分考虑这些方面。本研究的目的是调查中风后个体的病变位置以及与 LP 持续时间和严重程度的相关性。方法 使用体素病变症状图 (VLSM) 对 74 名右侧脑部病变患者（49 名有 LP，25 名无 LP）进行回顾性病例对照研究，以分析病变位置与 LP 严重程度之间的相关性。在 22 名 LP 患者的子样本中调查了持续时间。LP 是通过 Contraversive Pushing 量表诊断的。结果 与没有 LP 的个体相比，患有 LP 的个体表现出明显更大的病变尺寸。LP 严重性的 VLSM 分析未显示具有统计学意义的结果。VLSM 分析显示，额下回、海马、顶下回、缘上回、角回、颞叶皮层、矢状层和上纵束的 LP 持续时间较长具有统计学显着相关性。讨论与结论 LP 相关区域位于多感官网络中。发现与空间认知、记忆和注意力相关的额顶叶网络区域与持续时间和严重程度相关。调查结果，