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Development of saliva-based cardiac troponin I point-of-care test using alpha-amylase depletion: a feasibility study.
Coronary Artery Disease ( IF 1.8 ) Pub Date : 2023-06-05 , DOI: 10.1097/mca.0000000000001257
Roi Westreich 1 , Gal Tsaban 1 , Yoav Neumann 2 , Amjad Abu Salman 1 , Omri Braver 1 , Dana Braiman 1 , Tali Zamed 1 , Zipora Feiga Neuhaus 1 , Omer Deutsch 2 , Aaron Palmon 2 , Nimrod Maimon 1 , Doron Zahger 1 , Yigal Abramowitz 1
Affiliation  

Cardiac troponin (cTn) is the biomarker of choice for detection of myocardial injury. There is a great need for simple point-of-care (POC) troponin testing among patients with chest pain, mainly in the prehospital setting. The purpose of this study was to evaluate the presence of cardiac troponin I (cTnI) in saliva of patients with myocardial injury using alpha-amylase depletion technique.

中文翻译:

使用α-淀粉酶耗竭开发基于唾液的心肌肌钙蛋白 I 即时检验:一项可行性研究。

心肌肌钙蛋白 (cTn) 是检测心肌损伤的首选生物标志物。胸痛患者非常需要进行简单的床旁 (POC) 肌钙蛋白检测,主要是在院前环境中进行。本研究的目的是使用α-淀粉酶耗竭技术评估心肌损伤患者唾液中心肌肌钙蛋白 I (cTnI) 的存在。
更新日期:2023-06-05
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