This review explores the potential of using novel imaging approaches to deepen our understanding of descending modulatory mechanisms in pain, focussing on functional magnetic resonance imaging (fMRI) of the spinal cord and novel approaches to combining molecular and fMRI data. This review sheds light on the neural processes involved in pain modulation, paving the way for the development of targeted treatments.

中文翻译：

---

利用内源性疼痛控制机制的力量进行新型疗法：神经影像学的创新如何提供帮助？

本综述探讨了使用新型成像方法加深我们对疼痛下行调节机制的理解的潜力，重点关注脊髓的功能性磁共振成像 (fMRI) 以及结合分子和 fMRI 数据的新方法。这篇综述揭示了参与疼痛调节的神经过程，为开发靶向治疗铺平了道路。