The inability to support the growth and development of a mature fetus up to delivery results in significant human suffering. Current available solutions include adoption, surrogacy, and uterus transplantation. However, these options are subject to several ethical, religious, economic, social, and medical concerns. Ectogenesis is the process in which an embryo develops in an artificial uterus from implantation through to the delivery of a live infant. This current narrative review summarizes the state of recent research focused on human ectogenesis. First, a literature search was performed to identify published reports of previous experiments and devices used for embryo implantation in an extracorporeally perfused human uterus. Furthermore, studies fitting that aim were selected and critically evaluated. Results were synthesized, interpreted, and used to design a prospective strategy for future research. Therefore, this study suggests that full ectogenesis might be obtained using a computer-controlled system with extracorporeal blood perfusion provided by a digitally controlled heart–lung–kidney system. From a clinical perspective, patients who will derive significant benefits from this technology are mainly those women diagnosed with anatomical abnormalities of the uterus and those who have undergone previous hysterectomies, numerous abortions, and experienced premature birth. Ectogenesis is the complete development of an embryo in an artificial uterus. It represents the solutions for millions of women suffering from premature deliveries, and the inability to supply growth and development of embryos/fetuses in the womb. In the future, ectogenesis might replace uterine transplantation and surrogacy.

无法支持成熟胎儿的生长和发育直至分娩导致人类遭受巨大痛苦。目前可用的解决方案包括收养、代孕和子宫移植。然而，这些选择受到一些伦理、宗教、经济、社会和医学问题的影响。体外发育是胚胎在人造子宫中发育，从植入到生出活婴儿的过程。当前的叙述性评论总结了最近关注人类体外发生的研究状况。首先，进行文献检索以确定先前发表的用于体外灌注人类子宫中胚胎植入的实验和设备的报告。此外，还选择并严格评估了符合该目标的研究。结果被综合、解释并用于设计未来研究的前瞻性策略。因此，这项研究表明，使用计算机控制系统，通过数控心肺肾系统提供体外血液灌注，可以实现完全的体外发生。从临床角度来看，将从这项技术中获益的患者主要是那些被诊断患有子宫解剖异常的女性以及曾经接受过子宫切除术、多次流产和经历过早产的女性。体外发育是胚胎在人造子宫中的完全发育。它为数百万遭受早产以及无法在子宫内提供胚胎/胎儿生长和发育的妇女提供了解决方案。未来，体外生殖可能会取代子宫移植和代孕。