Many men age 50+ with HIV (MWH age 50+) are sexually active. However, little is known about the relationship between the number of sexual partners and patient-reported outcomes in this population. To help address this need, analyses were performed on data from the Aging with Dignity, Health, Optimism and Community cohort, an observational study of adults age 50+ with HIV. Of 876 MWH age 50+, 26.8% had 0 sexual partners in the past year, 27.9% had 1, 21.5% had 2-5, and 23.9% had >5. Men with one partner were significantly less lonely and less depressed than any other group (p < .01 for pairwise comparisons). Men with zero partners were more depressed than any other group. Linear regression controlling for race and relationship status showed men with one partner had lower levels of loneliness than any other group. They also had lower levels of depression than men with zero or more than than five sexual partners, although depression levels were not significantly different for men with one or with two to five partners. Linear regression also showed that men in relationships were less lonely and less depressed than men who were not in relationships, after controlling for race and number of sexual partners. Better understanding of the roles that number of sex partners and relationships play in the mental health of MWH age 50+ may help ameliorate the burden of loneliness and depression in this vulnerable population. ClinicalTrials.gov (Identifier: NCT04311554).

中文翻译：

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50 岁以上感染艾滋病毒的男性的性伴侣数量和患者报告的结果。

许多 50 岁以上感染艾滋病毒的男性（MWH 50 岁以上）性行为活跃。然而，人们对这一人群的性伴侣数量与患者报告的结果之间的关系知之甚少。为了帮助满足这一需求，我们对“有尊严、健康、乐观和社区的老龄化”队列的数据进行了分析，这是一项针对 50 岁以上感染艾滋病毒的成年人的观察性研究。在 876 名 50 岁以上 MWH 中，26.8% 的人过去一年有 0 个性伴侣，27.9% 有 1 个，21.5% 有 2-5 个，23.9% 有 > 5 个。与其他组相比，有一个伴侣的男性明显较少感到孤独和抑郁（成对比较时，p < .01）。零伴侣的男性比其他任何群体都更加抑郁。控制种族和关系状态的线性回归显示，有一个伴侣的男性比任何其他群体的孤独感都要低。与拥有零个或五个以上性伴侣的男性相比，他们的抑郁水平也较低，尽管与拥有一个或两到五个性伴侣的男性相比，抑郁水平没有显着差异。线性回归还表明，在控制种族和性伴侣数量后，处于恋爱关系中的男性比没有恋爱关系的男性更少孤独和抑郁。更好地了解性伴侣数量和性关系在 50 岁以上 MWH 心理健康中所扮演的角色可能有助于减轻这一弱势群体的孤独和抑郁负担。ClinicalTrials.gov（标识符：NCT04311554）。