Dedifferentiated fat cells (DFATs) isolated from mature adipocytes have a multilineage differentiation capacity similar to mesenchymal stem cells and are considered as promising source of cells for tissue engineering. Bone morphogenetic protein 9 (BMP9) and low-intensity pulsed ultrasound (LIPUS) have been reported to stimulate bone formation both in vitro and in vivo. However, the combined effect of BMP9 and LIPUS on osteoblastic differentiation of DFATs has not been studied.

中文翻译：

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低强度脉冲超声促进 BMP9 诱导大鼠去分化脂肪细胞的成骨细胞分化。

从成熟脂肪细胞中分离出的去分化脂肪细胞（DFAT）具有与间充质干细胞相似的多谱系分化能力，被认为是组织工程的有希望的细胞来源。据报道，骨形态发生蛋白 9 (BMP9) 和低强度脉冲超声 (LIPUS) 可在体外和体内刺激骨形成。然而，BMP9 和 LIPUS 对 DFAT 成骨细胞分化的联合作用尚未研究。